Detroit Lions @ Chicago Bears - The Lions are coming off their biggest win in possibly 2 decades, but the Bears are starting to roll under new QB Jay Cutler. Matt Forte should be able to get his game going, and the Lions are facing too much pressure to follow up win #1 in a hostile environment. Bears 23-12
Seattle Seahawks @ Indianapolis Colts - Seattle hasn't been as bad as it may seem (They do have the 10th Off and 11th Def), but they have trouble putting it all together for wins. Indianapolis however, does not. Peyton shined in primetime last week, and will continue padding his stats here. Colts 34-17
Cincinnati Bengals @ Cleveland Browns - The Browns are in a close competition with the Rams for worst team in the league, and with a new starting QB this week, things are looking worse than they have since their return. Cincinnati, however, could be 3-0, and is coming off a huge win that could give them momentum through the season. Bengals 38-6
Oakland Raiders @ Houston Texans - One of these teams will find the elixir to turn around their season in this game. Either Oakland's offense will take advantage of the Texans atrocious D, or the Texans D will dominate the Raiders O. Either way, this game could be more fun to watch than that Monday night atrocity that was the Panthers and Cowboys. Texans 41-31
Tennesee Titans @ Jacksonville Jaguars - Collins and his young group of receivers should be able to pick up their game here, and at the same time Mo-JoDrew may have a tough time running against the 2nd ranked D against the run. It'll come down to whether or not Garrard can get the job done through the air. Titans 20-14
New York Giants @ Kansas City Chiefs - Last week, the Giants shut down the Bucs, and they have the potential of doing it again here. The Chiefs however, had their best game of the season against the Ravens, so the Giants need to be careful not to fall into a trap. Giants 40-16
Baltimore Ravens @ New England Patriots - This will most likely end up the game of the weekend, and could be a preview of what we can expect in January. Flacco & Co. are on a roll, as are Brady & Co. Ravens 26-21
Tampa Bay Buccaneers @ Washington Redskins - *Insert facepalm icon here* The Buccaneers and Redskins are coming off what will be the worst games of each of their seasons, and need a win to earn a little respect among their fans, and save some jobs in the process. Someone has to win, right? Redskins 13-8
Buffalo Bills @ Miami Dolphins - You can throw away anything the Dolphins had acheived until now, and basically start over. With Pennington, they had a chance to compete. With Henne, they're starting their rebuild. The Wildcat probably won't be enough to remain competitive here. Look for the Bills to shut up T.O., and get him involved early. Bills 33-10
New York Jets @ New Orleans Saints - I think I made a mistake. Mark this down as the game of the weekend. The Jets get a chance to prove they're for real, and the Saints defense gets a chance to show that last week was no fluke. I'm thinking this game is decided with who plays better when the Jets have the ball. Saints 19-17
Dallas Cowboys @ Denver Broncos - Dallas is going to have to correct some of their mistakes, because Denver will not give them as many opportunities to steal the win. Denver's defense has played over their heads, and there's a chance they come to earth here. Most people miss that Orton has 0 INTs, and I don't think he'll throw any here. Broncos 24-17
St. Louis Rams @ San Francisco 49ers - I already covered how awful the Rams are, so I won't beat a dead horse. The Niners are looking to bounce back from the last second upset by the Vikes, and should find an easy road to victory here. 49ers 37-9
San Diego Chargers @ Pittsburgh Steelers - Both teams have had a lot of trouble running the ball, so it will come down to which QB can lead his team best. While Ben may be the better game mananger of the two, I'll take Rivers in a game where both guys will need to drop back 30-35 times. Chargers 28-20
Green Bay Packers @ Minnesota Vikings - The Packers are going to be hungry to get after Favre, and it could be they're undoing. The defense is good if they don't play into the head games, and can force a few turnovers. The Vikings defense is solid, and at home, Favre won't be playing against an angry crowd. Vikings 22-13