Actually when you think about it realistically, the Zig-Zag would be a painful thing to be hit with in a real life situation. Imagine someone that weighs around 230 pounds grabbing you by your hair or neck and driving you with a lot of force into the ground. Not only could the impact leave you with a possible concussion depending on what the surface is, but it could also send a shock down your spinal cord, temporarily leaving you numb. I've experienced something like it in a rugby match, when you land hard on your back and you lose all feeling for a moment, scary shit.
Yes, I do think about these things when watching wrestling. Sue me.
I agree on the "Cobra", it's all a comedic thing. The Skull Crushing Finale, is one move which when hit, makes me wonder why its a finisher in the first place. Really, all hes doing is tripping you while holding your hands up so that you hit the floor directly on your face. Done onto a chair or steel, fine, it could do some damage, but in a wrestling match it really doesn't look very strong.
The Worm by Scotty Too Hotty is an obvious move which was, much like Santino, simply for comedic reasons. The Bionic Elbow, used by Dusty Rhodes used to always make me wonder could it really but you down? I guess when hit with an elbow to the head, it could, but damn it looked weak. Oh, and he Leg Drop, made famous by one Hulk Hogan never really made any sense to me. He's putting his leg across your throat, once again in certain aspects its believble, but in others and more, it's just not!