His feud with R-Truth will likely culminate in a WrestleMania match. That may seem a long way off, but if you think about it, they'll likely eliminate each other in the Royal Rumble to build up the grudge. No way they get a singles match there. There's been talk of having both of them in the Elimination Chamber, and with neither winning that would again build up the grudge even further. The only thing left after that is WrestleMania... I'm on board if they want to stretch this out over the next 4 months. We don't get enough long-term feuds, and I can't think of a better way to make these two seem important. What else is Miz or Truth going to do at Mania?
After WrestleMania they'll likely have a few matches and tag encounters against each other on Raw. Maybe a rematch at Extreme Rules with a gimmick thrown in - they really like doing that. At whatever the next PPV is, I could see them involving both of them in some sort of contender's thing, or putting them BOTH in a title match. Basically, I think this feud will solidify them both as main event guys, and they won't be rid of each other fully until well into 2012. Miz will, at some point, be a WWE or World Champion again, and I wouldn't be surprised if it happens before the year is up. Before SummerSlam even... You never know what happens in the draft, if there is one.
My predicted schedule:
Royal Rumble: Miz participates in the Rumble match, but does not win.
Elimination Chamber: Miz participates in the title/chamber match, but does not win.
WrestleMania: Miz vs. R-Truth
Extreme Rules: Miz vs. R-Truth with some sort of "extreme gimmick"
Over the Limit: Miz is involved in the WWE title match, which will likely be a multi-man match involving Truth as well, if they stay on the same brand
Bragging Rights: If they do SvR, Miz will likely be on one of the teams
Money in the Bank: If he's not champion, he'll be in the MITB Ladder match
SummerSlam: Wouldn't doubt if Miz is WWE Champion by this time