Healing factor says he isnt allergic to that. Deadpool wins. Might even end up strapping a saddle on that sumbitch and getting a new pet that doubles as a mode of fuel efficient transportation....
Oh right, the healing factor. All the dragon needs to do is bite off half of Deadpool's body or char him to a crisp and the dragon can tout off to the next round. I love Deadpool, but the dude is the comedic punching bag of the Marvel universe.