If Alberto wins the title tomorrow (which I hope he doesn't), he would need a face to feud with. We've seen him feud with Rey and to some extent Edge, who has been the dominant presence as WHC challenger for two months. From there the obvious question is who would Alberto feud with?
They seem to be very high on Jackson, and have for some time. They had him win the ECW title on the final night so that he could hold it for five seconds, which signaled an apparent push, which was furthered with a dominant squash match against Jimmy Wang Yang (ever think you'd hear that name again?) on Smackdown before he got injured. They even moved him to the A show during the draft, despite that he wouldn't be returning for several months. Since returning, he's come back as a face and been pretty dominant on Raw. They seem to want him to go places, and now they've moved him to Smackdown so that he can have more of a role. Raw is ridiculously crowded with the Miz/Orton and Cena/Nexus angles right now, and the US champion is a face, so having him compete in that scene makes no sense.
In moving to Smackdown, I can see him getting over with a few dominant appearances, probably in squashes against the likes of Trent Baretta and Chavo. In the meantime, if Alberto wins the WHC, give him the spotlight for two weeks, make some claim about how no one can beat him and bring out Zeke for the interruption, setting up a match at the Rumble, in which Del Rio most likely retains by cheating/DQ/countout. From there, they're both in the EC, at which point Alberto probably loses the title, likely not to Zeke, but in the meantime, they can establish him as a serious threat in the upper mid-card. I seriously don't see him involved in a WHC match/feud at 'Mania.
If they go the mid-card title route, I don't see him feuding with Ziggler, as the size difference would make a squash the only "logical" result, and I doubt they'd want to go that route. If Kofi wins, the point is moot, but I could see a feud with Swagger being much more convincing and somewhat more balanced. I still see the former scenario as the most likely.
Random thought: since they just erased a match from tomorrow's card, does anyone think there's a chance of an impromptu filler match involving Jackson against someone like McIntyre?