I actually always liked the early seasons of Just Shoot Me, and David Spade. Yeah, sue me. Although the character of "Maya" on the show, in my opinion, is the single most unlikeable character in television history. How the fuck we're supposed to approve of this hypocritical, self-righteous, arrogant, close-minded, bitch of a woman, I'll never understand. She was a fucking cunt from episode one, and took the show down every time she was on. Luckily the characters of Nina, Elliot, Finch, and Brian Posehn as the mail guy were good enough to make the show amusing.
However, it loses to Beavis & Butthead in a landslide here. I still wonder to this day if all of my fellow stoner slackers of the 90s realize that Mike Judge was actually poking fun at them with the show, but nevertheless it was great and one that I continue to watch to this very day. It's pure physical and stupid humor at it's best, and the music videos add to it a nostalgia feeling for the 90s that makes the show addictive to someone like myself who has such fond memories of growing up in that decade.
Beavis & Butthead win here easily. Mike Judge's best work, bar none.