I think some of the veteran talent will have more runs on top, but I dont think they should just because they are finishing up soon. It has to make sense with the product.
Christian is not a concern of mine, he is in a good spot right now and has just turned heel, opening up several new possiblities for feuds and I am pretty sure that the CLB will have at least one more title run. I reckon Vince's views on him are changing and he can see that Christian is worth his ME spot.
Mysterio is a guy I hope does not get another world title reign, but I would not be shocked at all if he does. Kids still love him, he is a money making machine in merchandise and he is always over. I fully expect him to have the gold once again before he calls it a day.
Big Show is way past his prime now and seems to be out of the main event scene now. However, with his size he is always someone who could get back in the title mix pretty easily, so it is a possiblity he will be given another reign. I think its less likely than Rey though.
I dont think Kane will get another title run. I have a feeling his run last year was his "thank you" from management. I would be all for a heel Kane run on top though, and with the mask! I know it won't happen, but for personal nostalgia and MTFO moments, I would love to see masked Kane again, and he could go out the way he came in, as a masked monster.
If Jericho comes back he will almost certainly have at least 1 more reign. He is always going to be in the mix.
But the one I am almost 100% sure that will have another run on top is HHH. I fully expected him to beat Flairs 16 world titles when he was dominating a few years ago but age, injuries and other WWE roles have taken him out of the picture in the last couple of years. However, he is still one of the biggest names that the company has, can still go in the ring, and I truly hope we see The Game back on top, even for a short run before he retires. I think we will, I would be shocked if Vince does not give his son-in-law at least 1 more title reign. They dont seem to be as important to HHH as they once were, he seems to be happy in his role now but he certainly deserves it. He is one of the all time greats.
To the people who are suggesting Mark Henry? Are you mad? He may have become slightly more relevant, but he is not and never will be championship material. Yes, he has been with the company a long time but he has never been a draw, never had a great feud and would put on some of the worst title matches of all time. I could perhaps stomach a Henry mid-card title reign, and didnt mind his ECW run, but as a world champion? Hell no