Taker - I don't see why he couldn't have another reign like his most recent one, where he more or less only turns up for the PPV defences.
HHH - If he doesn't retire, then probably yes he will. HEll, even if he does retire i wouldn't put it past him not to come back a couple fo years later and win the belt from someone, just like Vince did in 1999. Speaking of Vince, he should be on this list too (lol).
Big Show - I could definitely see him winning it again. Show hasn't been champion since 2006 in ECW, and if we're talking about titles that mean something, he hasn't been since 2002! I could easily see Show getting the same sort of run Kane just had, as sort of a reward for all his hard work.
Kane - Sadly no. While i thought his title reign was fairly good, most people have shit on it relentlessly, so no i don't see them giving Kane another run.
Rey Mysterio - Should never have been champ to begin with.
CM Punk - Should be champion NOW, but yes i see Punk as being at the forefront of the title picture in the next 5-10 years, unless something goes truly wrong for him i.e. career ending injury.
John Cena - Of course he will, no doubt about it. I'd be literally shocked if he gets beaten by Miz at WM.
Randy Orton - Again, definitely, even if just to fill a gap when others get hurt a la Edge or Khali in '07.
Khali - Definitely not. The guy's used as a novelty act and just to get easy ratings in India. Santino has a better chance of being champion than he does.
Ziggler - Based on the facts that A) His one title reign was a give away one with no match to crown him champion, B) the strength of his performances in the last 6 months and C) the fact that he just got moved back to Raw, the 'A' brand, i'd say it's a safe bet that Ziggler will get another title run.
Sheamus - Again, don't see why not. Can't understand the direction they're going with him currently, but he got 2 title reigns out of literally nowhere and did well with them, so why not try giving him a reign with a proper build to it next time?
Swagger - Again, much like Sheamus, i see no reason why he couldn't get another title run, but he'll have to do a LOT of work to get them to consider him as a potential champion again.
Edge - If he must have another reign, then yeah, i guess he will.
Miz - Definitely. This is the one i'm most certain of. If Meth Hardy can get 2 title runs and barely even be on TV when he's champion, then the promo wizard that Miz is, should be at the top of the list for 'New World Champions'.