Going with Bioshock here, I've never heard of Syndicate, but it looks to be in the same vein as Starcraft. Judging from the fact that
1. I've never heard of it
2. Strategy games genre as a whole really isn't my first pick when it comes to games (more of a racing games type of person)
This tells me that Syndicate was really never that popular even in its own genre. When people think of great strategy games World of Warcraft, Starcraft, and Pikmin are usually the first games to come to mind.
I've played bioshock a few times, it's a good shooter, not my favorite but its solid. It's enough to get my vote against Syndicate.