Not really, but you have to remember that the actual process of getting into an arena these days is a lot different to the days of heels being stabbed etc. Incident's like Monica Seles being stabbed in the 90's really brought the hammer down on what people could take into arenas and then incidents like Dimebag Darrell being shot and 9/11 tightened it any more.
Wrestlers are at a physical risk any time they are in the space of the fans, you may see that a little less for a while but if anything Punk showed how to deal with it rather than do anything to cause a problem when he slapped the guy... that it happened to be the wrong guy is immaterial to him... If you invade the ring, you expect to get hurt... if the wrestlers are close to you in the crowd, it's a privilege and if someone attacks or even takes a liberty, they should be expecting to be hurt.
When Jericho popped the stupid bitch out in the street, it was a little more serious in some ways as there was a mob situation and while he wasn't "in his place of business" and protected by the E's "We reserve the right to terminate the show" he handled it.
Generally the talent are able to hold their own, maybe not against 2 or 3 people but if one fan tries they can at least defend themselves better than the man on the street perhaps could. It's also unusual for a talent to be in the crowd on their own. Punk was the only time I really remember it being of that nature... normally it's two guys brawling or the Shield as a unit entering... if anything happened there are two guys there who might suddenly break character, but safety of the workers would be assured.
In an arena at the start of every show they have that announcement I mentioned... it always jars with me cos it's like "really? you really THINK that's gonna happen? You really THINK that you're gonna do something so inflammatory tonight?" but at the moment it probably could and that's their only major worry... the old "if Cena wins we riot" was a joke, had they done so there would have been serious consequences... indeed anyone who disrupts the show in theory could be liable to lawsuits or criminal problems and remember the camera can identify you, much as they can for throwing a coin in a football match...
They have to decide how much "disruption" would constitute that now... is a Punk' sign or shirt now a no-no, if so it's gonna piss people off and cause issues... at one point they were literally handing out freebie shirts to people wearing something with the old WWF logo on it... do they start doing that... soon that could be an issue as Punk fans en-masse do it to get a free shirt...
Rhe chants will continue they can't eject someone for them and if will be exacerbated if signs, t-shirts etc are taken away without the free shirt... soon it becomes a bigger issue than if they accede to what Punk perhaps wants. At this stage we don't know WHAT is going on... if it's a work it's the most interesting since Montreal (Bret never did sue over that creative control) but if it's real they are almost better off giving Punk a new deal, having him show up to open wrestlemania, maybe disrupt/jaw with Hogan and they set 31's main event in stone as him facing the champion...
There will come a point where that is probably preferable to the disruption or backlash... but of course a lot can happen in one year and Phil wouldn't be able to "stay out of the ring" for the whole year, so if someone "accidentally" injured him in January they'd still have time to "recover" the show with a new main event.