Damn, I am surprised Malcolm in the Middle has made it this far. My hat goes off to it. That being said, The correct vote is Scrubs. The answer is because it is practically an institution for this decade. When people think of modern day sitcoms, Scrubs has to come to mind. It is such a juggernaut. Bill Lawrence really out did himself coming off the heels of the very successful Spin City.
It is no secret that I am a fan of Spin City but I would easily consider Scrubs an equal and probably far superior to Spin City. The chemistry between the cast is great. They all really know how to play off of one another. John C. McGinley really shines as the overly sarcastic, narcissistic to perfection. Zach Braff is awesome playing the attention seeking, over achiever. Everyone really knows how to fit into their roles. They can all act goofy yet really bring the drama when it is needed.
The soundtrack is one of the best for any show, at any time throughout history. The show plays so much on music and emotion and it does it so well.
They had a star wars episode. Just about every great show has had a Star Wars parody episode.
Vote for Scrubs.