Wow this is a tough one here. I was never a fan of Father Knows Best, just never really caught on with me past the maybe ten minutes of the show I've seen. The Jetsons is a classic television show and one that any child has probably grown up watching, no matter what era they were born in. Remember the Jetsons-Flinstones crossover movie? Yeah, that was the greatest 90 minutes of my life.
But, my vote is going to Dobie Gillis once again just as it did last round, if only to enlighten more people to what a cool little show that was. Seriously groundbreaking stuff at the time, this was the first TV show really made for a younger audience instead of the middle aged people. It was like rock and roll in the world of tame pop that was the rest of the sitcom landscape. Definitely gets my vote here, great little show.